22 January 2021 (Friday) - Anti-Kp(a)

I had a rather fraught early shift today… in retrospect it wasn’t that busy, but having had a quiet one yesterday I had been hoping for more of the same. But within an hour or so of starting work I had detected an atypical blood group antibody and had identified it.
Anti-Kp(a) is rather obscure as antibodies go… with only two per cent of the population (at best) carrying the antigen it can be a challenge for those who produce antibody panels to be able to include it in their repertoire. I must admit I can’t remember having identified one myself before.

Directed at an antigen of the Kell blood group system, anti-Kp(a) can cause both haemolytic blood transfusion reactions and haemolytic disease of the foetus and newborn. Rather than copying and pasting (which would fool no one, here’s a few references…


 and loads more can be found in less than thirty seconds with a search on Google.
I learned something today…

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