I had a
rather fraught early shift today… in retrospect it wasn’t that busy, but having
had a quiet one yesterday I had been hoping for more of the same. But within an
hour or so of starting work I had detected an atypical blood group antibody and
had identified it.
Anti-Kp(a)
Anti-Kp(a)
is rather obscure as antibodies go… with only two per cent of the population (at
best) carrying the antigen it can be a challenge for those who produce
antibody panels to be able to include it in their repertoire. I must admit I
can’t remember having identified one myself before.
Directed at an antigen of the Kell blood group system, anti-Kp(a) can cause both haemolytic blood transfusion reactions and haemolytic disease of the foetus and newborn. Rather than copying and pasting (which would fool no one, here’s a few references…
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850705/
https://www.ncbi.nlm.nih.gov/books/NBK2270/
http://www.ijbti.com/archive/2013-archive/100012IJBTIKQR2013-rossi/100012IJBTIKQR2013-rossi.pdf
and loads
more can be found in less than thirty seconds with a search on Google.
I learned
something today…
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