Here’s something new… https://en.wikipedia.org/wiki/Pearson_syndrome
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Kirk James T X1234567 25.12.14 M DCCNT Dr Kildare
H,18.4314853.Y U
31.07.18 Clin. det. pearson
syndrome
DIFF Microscopy (Maids)
Diagnosis
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HBM WBCM
PLT HCT RBCM
MCVM MCHM MCHCM
RDW N
160518 F 65 3.32
54 0.186 1.99
93.5 32.7 349
18.0 0.49
120618 F 92 3.62
81 0.276 2.81
98.2 32.7 333
22.9 0.66
030718 F 93 4.43
78 0.282 2.66
106.0 35.0 330 0.82
310718 F 89 4.34
37 0.257 2.48
103.6 35.9 346
20.1 0.62
L M
E B RETP
RETA IRF NUC
GF ESR
160518 F 2.57 0.23
0.02 0.01 2.8
56.10 24.6
120618 F 2.60 0.26
0.08 0.02
030718 F 3.32 0.21
0.07 0.01
310718 F 3.41 0.22
0.08 0.01 1.2
28.80 16.0
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WBCM N
L M E
B MET MYE
PRO BLAST NUC
(3) (2)
(1) (.) (0)
(4) (5) (6)
(9) #(7)
0 0
0 0 0
0 0 0
0 0 0
4.3 0.0
0.0 0.0 0.0
0.0 0.0 0.0
0.0 0.0 0.0
Note ongoing neutropenia and thrombocytopenia
Blood film shows anisopoikilocytosis with some polychromasia
and some spherocytes seen.
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Pearson syndrome is a mitochondrial disease characterized by
sideroblastic anemia and exocrine pancreas dysfunction. Other clinical features
are failure to thrive, pancreatic fibrosis with insulin-dependent diabetes and
exocrine pancreatic deficiency, muscle and neurologic impairment, and,
frequently, early death. It is usually fatal in infancy. The few patients who
survive into adulthood often develop symptoms of Kearns-Sayre syndrome.
It is caused by a deletion in mitochondrial DNA. Pearson syndrome is very
rare, less than hundred cases have been reported in medical literature
worldwide.
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