6 May 2022 (Friday) - Transfusion Evidence Library Update

The nice people at the Transfusion Evidence Library sent a missive today focussing on International Thalassaemia Day (this coming weekend).

I quite like having a theme to the articles they send – I found it rather focussed my poor brain.

Top Article

Selected Articles

The effect of iron chelation therapy on overall survival in sickle cell disease and beta-thalassemia: a systematic review.Ballas, S.K, et al. (2018). American Journal of Hematology.

Systematic literature review of the burden of disease and treatment for transfusion-dependent beta-thalassemia.Betts, M., et al. (2019). Clinical Therapeutics.

A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent beta-Thalassemia.Cappellini, M.D., et al. (2020). New England Journal of Medicine.

Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews.Fortin, P.M., Hopewell, S., and Estcourt, L.J., (2018). The Cochrane Database of Systematic Reviews. 

Red blood cell alloimmunisation in transfusion-dependent thalassaemia: a systematic review.Franchini, M., et al. (2019). Blood Transfusion.

Evidence-based interventions implemented in low-and middle-income countries for sickle cell disease management: A systematic review of randomized controlled trials.Gyamfi, J., et al. (2021). PloS One

COVID-19 and Hemoglobinopathies: A Systematic Review of Clinical Presentations, Investigations, and Outcomes.Lee, J.X., et al. (2021). Frontiers in Medicine.

Gene therapy for sickle cell disease.Olowoyeye, A., and Okwundu, C.I., (2020). The Cochrane Database of Systematic Reviews.

Interventions for chronic kidney disease in people with sickle cell disease.Roy, N.B, et al. (2017). The Cochrane Database of Systematic Reviews.

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