25 November 2021 (THursday) - Transfusion Evidence Alert Update

The Transfusion Evidence Alert email arrived today. As always there was too much to take in at a single sitting, but it is all good stuff. And much of it relevant to what I do.


Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.Estcourt, L.J., et al. (2021). JAMA.PICO Summary available



Tranexamic acid for the prevention of postpartum hemorrhage in women undergoing cesarean delivery: an updated meta-analysis.Bellos, I., et al. (2021). American Journal of Obstetrics and Gynecology. [Record in progress]

Promoting awareness of donation-related iron depletion among high risk blood donors.France, J.L., et al. (2021). Transfusion. [Record in progress]

High dose coupled plasma filtration and adsorption in septic shock patients. Results of the COMPACT-2: a multicentre, adaptive, randomised clinical trial.Garbero, E., et al. (2021). Intensive Care Medicine.

Albumin in the management of hepatic encephalopathy: a systematic review and meta-analysis.Is, B., et al. (2021). Annals of Hepatology. [Record in progress]

Erythropoietin monotherapy for neuroprotection after neonatal encephalopathy in low-to-middle income countries: a systematic review and meta-analysis.Ivain, P., et al. (2021). Journal of Perinatology: Official Journal of the California Perinatal Association.

Prothrombin Complex Concentrate for Trauma Induced Coagulopathy: A Systematic Review and Meta-Analysis.Kao, T.W., et al. (2021). Journal of Acute Medicine.

Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a pre-planned substudy in a sample of CRASH-3 trial patients.Mahmood, A., et al. (2021). Emergency Medicine Journal

A pilot randomized clinical trial of cryopreserved versus liquid-stored platelet transfusion for bleeding in cardiac surgery: The cryopreserved versus liquid platelet-New Zealand pilot trial. McGuinness, S., et al. (2021). Vox Sanguinis. [Record in progress]



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