29 October 2021 (Friday) - Transfusion News Update


The nice people at Transfusion News sent their update today.  A couple of snippets about platelet transfusions. Not too much for me to take in this time…

Pathogen Reduced Platelets are Non-Inferior to Conventional Platelets for Hematology Patients

October 28, 2021Results for the PIPER Phase 4 study of psoralen-UVA pathogen reduced platelets (PRPC) (Cerus Corporation) following transfusion were recently presented at the 2021 Annual AABB meeting. In this prospective, open-label, two-arm study at 15 U.S. hospitals, 1068 hematology-oncology platelet-dependent patients (mean age, 57.0 years) received PRPC, and 1223 comparable patients (mean age, 50.6 years) received conventional platelet concentrates (CPC). [Read More]


Cold Storage Affects Platelet Function and Glycoprotein VI Levels

October 20, 2021Maintaining an adequate supply of platelets is laborious and costly since they can only be stored for 5 to 7 days at room temperature and require additional bacterial testing. In the 1960s and 1970s, platelets were stored at 1-6° C, but circulation time of cold-stored platelets is very short and the practice was abandoned in the 1980s. Some studies, however, suggest that cold storage of platelets might actually preserve their hemostatic function and may be best for actively bleeding patients. [Read More]

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