14 October 2021 (Thursday) - Transfusion News Update

The nice people at Transfusion News sent their update today. Much of this is focussing on what happens to the samples that we send to the reference lab… but it is as well to know what the are getting up to…

 RBC Transfusions and Alloimmunization in Patients Taking Daratumumab

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October 12, 2021
Daratumumab (Dara), an anti-CD38 monoclonal antibody, was approved by the U.S. Food and Drug Administration (FDA) in 2015 for use in patients with hematologic malignancies. Compared to normal lymphoid and myeloid cells, multiple myeloma cells express high levels of CD38 making these cancerous cells targets for Dara. Dara, however, also binds to RBCs which express CD38, thus interfering with antibody screens, antibody identification, and other serological tests. [Read More]
Join us to learn how an International Reference Laboratory resolves cases with complex antibody identification
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In this new Transfusion Science Webinar, Shane Grimsley, Manager of the Red Cell Reference Laboratory at the International Blood Group Reference Laboratory (IBGRL), based in Bristol, UK, will show us how complex cases can be resolved and in particular, will discuss the many tools that are available for the resolution of complex antibody investigations. [Register Now]

The Mighty MMA! with Sandy Nance
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October 13, 2021 | BBGuy Podcast
CE episode! When red cell alloantibodies are unpredictable, the monocyte monolayer assay can clear things right up! Sandy Nance explains this very useful test. [Listen Now]
Listen on Apple Podcast Get It on Google Podcasts Spotify

Fear and Anxiety Associated with Attrition of First-Time Donors
October 6, 2021
In order to tease apart whether fear and anxiety in first-time blood donors actually led to fewer return donations, researchers followed 1479 first-time blood donors (67.9% female; mean age, 19.3 years) longitudinally over 14 months. First-time donors were invited to complete a survey one week following their first blood donation and again six weeks later. [Register Now]
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