3 May 2021 (Monday) - A.S.H. update

The nice people at the American Society of Hematology sent their update today 0 there was quite a lot to it…

The just-published May issue provides an update on gene therapies in hematology, demystifies RNA sequencing, and more!

Spotlight Gene Therapy: The Comeback Kid of Hematology Treatments? Despite slow progress and unexpected setbacks, the future of gene therapy remains bright. Pulling Back the Curtain In this edition, Craig Cole, MD, speaks about empowering patients to make treatment decisions, targeting racial disparities in myeloma, and more.

Viewpoints Editor’s Corner: All Those YESterdays Aaron Gerds, MD, shares his strategies for deciding which opportunities to seize and which to pass up in favor of maintaining work-life balance. Letters to the Editor: How Can the Myeloma Community Reduce Disparities in Care? In response to recent study coverage, hematologists discuss the growing body of literature drawing attention to the inequities in myeloma care. A Day in the Life: Transfusion Medicine as Team Sport Justin Kreuter, MD, takes a break from teaching and clinical duties to walk us through a typical day in the life of a pathologist specializing in transfusion medicine. Education Hematologica Obscura Hemophagocytic lymphohistiocytosis: Would you know it if you saw it? You Make the Call This month, Morie A. Gertz, MD, discusses whether a mostly asymptomatic patient with amyloidosis should receive systemic therapy. Demystifying the Lab RNA sequencing is already providing insights in cancer research, from identifying clinical biomarkers to helping better characterize disease subtypes, but experts say they are only beginning to unlock its potential. News ASH Directions ASH releases FAQ resource for thrombosis with thrombocytopenia syndrome, ASH News Daily seeks 2021 authors, and more. The Society Pages Senate confirms surgeon general and assistant secretary for health, HVO presents Golden Apple Awards, and more. Latest & Greatest FDA Commissioner and CIO Amy Abernethy, MD, PhD, resigns, FDA reevaluates accelerated approvals of cancer treatments, and more. From the Blood Journals Reduced Calf Muscle Pump Function Predicts VTE and Mortality Risk Adding Brentuximab Vedotin to Chemotherapy Improves Outcomes in Pediatric ALK-Positive ALCL Lenalidomide and Dexamethasone for Older Patients With Multiple Myeloma: Less Is More Outcomes After ABO-Incompatible Platelet Transfusions in Patients With Intracerebral Hemorrhage Why Are Individuals with Blood Group A at Higher Risk of COVID-19? Characterizing Complications Among Infants and Toddlers With von Willebrand Disease Literature Scan Research from other top journals, including: Idecabtagene Ciloleucel Induces Deep Responses in Relapsed/Refractory Multiple Myeloma High- and Low-Dose Rivaroxaban Versus Aspirin for Women With VTE and Heavy Menstrual Bleeding R2CHOP Benefits Patients With Untreated Diffuse Large B-Cell Lymphoma, Regardless of Subtype Detection of Platelet-Activating Antibodies Necessary to Diagnose HIT in Patients With COVID-19 On Location Advances in oncology from the AACR Annual Meeting, including: PATHFINDER: Avapritinib Induces Rapid Responses in Advanced Systemic Mastocytosis Evaluating a New Bispecific CAR T-Cell Therapy for B-Cell Lymphomas Copanlisib Plus Rituximab Improves Progression-Free Survival in Indolent Non-Hodgkin Lymphoma