17 March 2021 (Wednesday) - Transfusion Evidence Alert Update

The Transfusion Evidence Alert email arrived in my in-box today. Probably (definitely) too much to take in at once, but unusually (at first sight) this lot seems of more peripheral than direct interest. But something for nothing is always worth having…

Top 10 new articles: March 2021

Each month, the NHS Blood and Transplant Systematic Review Initiative provides an overview of the most important new publications in transfusion medicine. All content is sourced from the Transfusion Evidence Library. COVID-19 publications are included in this alert.



Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Major Cardiovascular Events Among Patients With Acute Myocardial Infarction and Anemia: The REALITY Randomized Clinical Trial.
Ducrocq, G., et al. (2021). Jama.
PICO Summary available



Impact of treating iron deficiency, diagnosed according to hepcidin quantification, on outcomes after a prolonged ICU stay compared to standard care: a multicenter, randomized, single-blinded trial.
Lasocki, S., et al. (2021). Critical care.

Comparison of Blood-Conserving and Allogenic Transfusion-Sparing Effects of Antifibrinolytics in Scoliosis Correction Surgery.
Ramkiran, S., et al. (2020). Anesthesia, Essays and Researches.

An epitope-based approach of HLA-matched platelets for transfusion: a noninferiority crossover randomized trial.
Marsh, JC., et al. (2021). Blood.

The Impact of Pre-Hospital TXA on Mortality among Bleeding Trauma Patients: A Systematic Review and Meta-Analysis.
Almuwallad, A., et al. (2021). The Journal of Trauma and Acute Care Surgery. [Record in progress]

Economic Analyses of Pathogen-Reduction Technologies in Blood Transfusion: A Systematic Literature Review.
LaFontaine, PR., et al. (2021). Applied Health Economics and Health Policy.

Is There a Role for Tranexamic Acid in Upper GI Bleeding? A Systematic Review and Meta-Analysis.
Burke, E., et al. (2021). Surgery Research and Practice.

Quality of evidence-based guidelines for platelet transfusion and use: A systematic review.
Al-Riyami, AZ., et al. (2021). Transfusion.

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