12 February 2017 (Sunday) - Childhood AML

This picture appeared in the Facebook “Hematology Interest Group” today. The cation was “identify the cells”.
Clearly the white cells are monocytoid; I would say monoblasts. However the red cells don’t look right; hypochromic with anisocytosis, and is there thrombocytopenia?

A few days later (I like being able to blog this retrospectively) some clinical information was given:
A one year infant presented with hyperleukocytosis (120k) ,thrombocytopenia , anemia, arthritis HSM. Morphological diagnosis AML-M5b , most of the cells present were promonocytes that accounted as blast equivalents.
Rather a horrible thing in a one year old…

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