16 April 2020 (Thursday) - Transfusion Evidence Alert email

The Transfusion Evidence Alert email arrived in my in-box today. Sepsis related anaemia, transfusion requirement of a combat-medic, beta-thalassaemia…

ARTICLE OF THE MONTH The effect of tranexamic acid by baseline risk in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients  FX Ageron, et al. Br J Anaesth 2020. PICO Summary available

TOP ARTICLES Sepsis-related anemia in a pediatric intensive care unit: transfusion-associated outcomes M Elshinawy, et al, Transfusion 2020. PICO Summary Application of Different Commercial Tourniquets by Laypersons: Would Public-access Tourniquets Work Without Training? RC Portela, et al. Acad Emerg Med 2020 PICO Summary Combat Medic Testing of a Novel Monitoring Capability for Early Detection of Hemorrhage NJ Koons, et al.The journal of trauma and acute care surgery 2020 PICO Summary Iron Chelation in Transfusion-Dependent Patients With Low- to Intermediate-1-Risk Myelodysplastic Syndromes: A Randomized Trial E Angelucci, et al. Ann Intern Med 2020 PICO Summary A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent beta-Thalassemia MD Cappellini, et al. N Engl J Med 2020 PICO Summary A systematic review and meta-analysis of traumatic intracranial hemorrhage in patients taking prehospital antiplatelet J Alvikas, et all. The journal of trauma and acute care surgery 2020 PICO Summary The effect of restrictive versus liberal transfusion strategies on longer-term outcomes after cardiac surgery: a systematic review and meta-analysis with trial sequential analysis HH Kashani, et al. Canadian journal of anaesthesia 2020 PICO Summary The effect of fibrinogen concentrate on postoperative blood loss: A systematic review and meta-analysis of randomized controlled trials Ng KT, et al. J Clin Anesth 2020 PICO Summary Prognostic factors for VTE and Bleeding in Hospitalized Medical Patients: a systematic review and meta-analysis AJ Darzi et al.Blood 2020 PICO Summary